Bioenergetic dysfunction in Huntington's disease human cybrids

In this work we studied the mitochondrial-associated metabolic pathways in Huntington's disease (HD) versus control (CTR) cybrids, a cell model in which the contribution of mitochondrial defects from patients is isolated. HD cybrids exhibited an interesting increase in ATP levels, when compared...

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Bibliographic Details
Main Author: Ferreira, IL (author)
Other Authors: Cunha-Oliveira, T (author), Nascimento, MV (author), Ribeiro, M (author), Proença, MT (author), Januário, C (author), Oliveira, CR (author), Rego, AC (author)
Format: article
Language:eng
Published: 2011
Subjects:
Doença de Huntington
Células Híbridas
Online Access:http://hdl.handle.net/10400.4/1108
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/1108

Internet

http://hdl.handle.net/10400.4/1108

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