Bioenergetic dysfunction in Huntington's disease human cybrids

In this work we studied the mitochondrial-associated metabolic pathways in Huntington's disease (HD) versus control (CTR) cybrids, a cell model in which the contribution of mitochondrial defects from patients is isolated. HD cybrids exhibited an interesting increase in ATP levels, when compared...

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Detalhes bibliográficos
Autor principal: Ferreira, IL (author)
Outros Autores: Cunha-Oliveira, T (author), Nascimento, MV (author), Ribeiro, M (author), Proença, MT (author), Januário, C (author), Oliveira, CR (author), Rego, AC (author)
Formato: article
Idioma:eng
Publicado em: 2011
Assuntos:
Texto completo:http://hdl.handle.net/10400.4/1108
País:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/1108