OCT-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, CDX2 in gastric cells

Intestinal metaplasia (IM) is a preneoplastic lesion of the stomach in which there is transdifferentiation of the gastric mucosa to an intestinal phenotype. The caudal-related homeobox gene CDX2 encodes an intestine-specific transcription factor crucial for the regulation of proliferation and differ...

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Bibliographic Details
Main Author: Raquel Almeida (author)
Other Authors: Almeida, J (author), Shoshkes, M (author), Mendes, N (author), Mesquita, P (author), Silva, E (author), Van Seuningen, I (author), Celso Reis (author), Santos-Silva F (author), David L (author)
Format: article
Language:eng
Published: 2005
Subjects:
Online Access:https://hdl.handle.net/10216/1891
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/1891