OCT-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, CDX2 in gastric cells
Intestinal metaplasia (IM) is a preneoplastic lesion of the stomach in which there is transdifferentiation of the gastric mucosa to an intestinal phenotype. The caudal-related homeobox gene CDX2 encodes an intestine-specific transcription factor crucial for the regulation of proliferation and differ...
Autor principal: | |
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Outros Autores: | , , , , , , , , |
Formato: | article |
Idioma: | eng |
Publicado em: |
2005
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Assuntos: | |
Texto completo: | https://hdl.handle.net/10216/1891 |
País: | Portugal |
Oai: | oai:repositorio-aberto.up.pt:10216/1891 |