Increased encapsulation efficiency of methotrexate in liposomes for rheumatoid arthritis therapy

Methotrexate (MTX) is a common drug used to treat rheumatoid arthritis. Due to the excessive side effects, encapsulation of MTX in liposomes is considered an effective delivery system, reducing drug toxicity, while maintaining its efficacy. The ethanol injection method is an interesting technique fo...

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Bibliographic Details
Main Author: Guimarães, Diana Isabel Pereira (author)
Other Authors: Noro, Jennifer Martins (author), Loureiro, Ana Isabel Sá (author), Lager, Franck (author), Renault, Gilles (author), Cavaco-Paulo, Artur (author), Nogueira, Eugénia (author)
Format: article
Language:eng
Published: 2020
Subjects:
liposomes
methotrexate
encapsulation
pre-concentration ethanol injection method
rheumatoid arthritis
Science & Technology
Online Access:http://hdl.handle.net/1822/71034
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/71034

Internet

http://hdl.handle.net/1822/71034

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