Contact sensitizers downregulate the expression of the chemokine receptors CCR6 and CXCR4 in a skin dendritic cell line

Chemokines are involved in the control of dendritic cell (DC) trafficking, which is critical for the immune response, namely in allergic contact dermatitis (ACD). In this work, we investigated by flow cytometry the effect of the contact sensitizers 2,4-dinitrofluorobenzene (DNFB), 1,4-phenylenediami...

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Bibliographic Details
Main Author: Cruz, MT (author)
Other Authors: Gonçalo, Margarida (author), Paiva, A (author), Morgado, JM (author), Figueiredo, A (author), Duarte, CB (author), Lopes, MC (author)
Format: article
Language:eng
Published: 2010
Subjects:
Dermatite de Contacto Alérgica
Dinitrofluorobenzeno
Fenilenodiamina
Receptores CCR6
Receptores CXCR4
Níquel
Online Access:http://hdl.handle.net/10400.4/753
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/753

Internet

http://hdl.handle.net/10400.4/753

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