The era of RNA interference medicines: the clinical landscape of synthetic gene silencing drugs
ABSTRACT - Therapeutic oligonucleotides, such as small interfering RNAs (siRNAs), provide a simple and effective tool to modulate the expression of any gene. siRNAs harness the RNA interference (RNAi) pathway to degrade disease-associated messenger RNAs (mRNAs). The inherent sequence specificity and...
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| Formato: | article |
| Idioma: | eng |
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2020
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| Texto completo: | http://hdl.handle.net/10400.21/11331 |
| País: | Portugal |
| Oai: | oai:repositorio.ipl.pt:10400.21/11331 |