Application of locked nucleic acid-based probes in fluorescence in situ hybridization

Fluorescence in situ hybridization (FISH) employing nucleic acid mimics as probes is becoming an emerging molecular tool in the microbiology area for the detection and visualization of microorganisms. However, the impact that locked nucleic acid (LNA) and 2'-O-methyl (2'-OMe) RNA modificat...

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Bibliographic Details
Main Author: Sílvia Fontenete (author)
Other Authors: Daniel Carvalho (author), Nuno Guimarães (author), Pedro Madureira (author), Céu Figueiredo (author), Jesper Wengel (author), Nuno Filipe Azevedo (author)
Format: article
Language:eng
Published: 2016
Online Access:https://hdl.handle.net/10216/103061
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/103061