The effects of old and recent migration waves in the distribution of HBB*S globin gene haplotypes

Abstract Sickle cell hemoglobin is the result of a mutation at the sixth amino acid position of the beta (β) globin chain. The HBB*S gene is in linkage disequilibrium with five main haplotypes in the β-globin-like gene cluster named according to their ethnic and geographic origins: Bantu (CAR), Beni...

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Detalhes bibliográficos
Autor principal: Lindenau,Juliana D. (author)
Outros Autores: Wagner,Sandrine C. (author), Castro,Simone M. de (author), Hutz,Mara H. (author)
Formato: article
Idioma:eng
Publicado em: 2016
Assuntos:
Texto completo:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000400515
País:Brasil
Oai:oai:scielo:S1415-47572016000400515