Studies on terrein as a new class of proteasome inhibitors

The proteasome is an intracellular multicatalytic protease involved in the cell cycle regulation, signaling response, antigen presentation and apoptosis. Since proteasome inhibitors promote cell death by apoptosis, they have been proposed as new anti-tumoral drugs. Terrein, a secondary metabolite se...

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Bibliographic Details
Main Author: Demasi,M. (author)
Other Authors: Felicio,A. L. (author), Pacheco,A. O. (author), Leite,H. G. (author), Lima,C. (author), Andrade,L. H. (author)
Format: article
Language:eng
Published: 2010
Subjects:
anti-tumoral drugs
proteasome inhibitors
apoptosis
cyclopentenone derivatives
terrein
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000200015
Country:Brazil
Oai:oai:scielo:S0103-50532010000200015

Internet

http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000200015

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