Studies on terrein as a new class of proteasome inhibitors

The proteasome is an intracellular multicatalytic protease involved in the cell cycle regulation, signaling response, antigen presentation and apoptosis. Since proteasome inhibitors promote cell death by apoptosis, they have been proposed as new anti-tumoral drugs. Terrein, a secondary metabolite se...

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Detalhes bibliográficos
Autor principal: Demasi,M. (author)
Outros Autores: Felicio,A. L. (author), Pacheco,A. O. (author), Leite,H. G. (author), Lima,C. (author), Andrade,L. H. (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Texto completo:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000200015
País:Brasil
Oai:oai:scielo:S0103-50532010000200015