Antitumor activities and cellular changes induced by TrkB inhibition in medulloblastoma

Neurotrophins are critically involved in regulating normal neural development and plasticity. Brain-derived neurotrophic factor (BDNF), a neurotrophin that acts by binding to the tropomyosin receptor kinase B (TrkB) receptor, has also been implicated in the progression of several types of cancer. Ho...

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Bibliographic Details
Main Author: Thomaz, Amanda Cristina Godot (author)
Other Authors: Pinheiro, Kelly de Vargas (author), Souza, Bárbara Kunzler (author), Gregianin, Lauro José (author), Brunetto, Algemir Lunardi (author), Brunetto, Andre Tessainer (author), Farias, Caroline Brunetto de (author), Jaeger, Mariane da Cunha (author), Ramaswamy, Vijay (author), Nor, Carolina (author), Taylor, Michael David (author), Roesler, Rafael (author)
Format: other article
Language:eng
Published: 2019
Subjects:
Receptor trkB
Meduloblastoma
Fator neurotrófico derivado do encéfalo
Brain-derived neurotrophic factor
Tropomyosin receptor kinase B
Neurotrophin
Medulloblastoma
Brain tumor
Online Access:http://hdl.handle.net/10183/197545
Country:Brazil
Oai:oai:www.lume.ufrgs.br:10183/197545

Internet

http://hdl.handle.net/10183/197545

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