Antitumor activities and cellular changes induced by TrkB inhibition in medulloblastoma

Neurotrophins are critically involved in regulating normal neural development and plasticity. Brain-derived neurotrophic factor (BDNF), a neurotrophin that acts by binding to the tropomyosin receptor kinase B (TrkB) receptor, has also been implicated in the progression of several types of cancer. Ho...

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Detalhes bibliográficos
Autor principal: Thomaz, Amanda Cristina Godot (author)
Outros Autores: Pinheiro, Kelly de Vargas (author), Souza, Bárbara Kunzler (author), Gregianin, Lauro José (author), Brunetto, Algemir Lunardi (author), Brunetto, Andre Tessainer (author), Farias, Caroline Brunetto de (author), Jaeger, Mariane da Cunha (author), Ramaswamy, Vijay (author), Nor, Carolina (author), Taylor, Michael David (author), Roesler, Rafael (author)
Formato: other article
Idioma:eng
Publicado em: 2019
Assuntos:
Receptor trkB
Meduloblastoma
Fator neurotrófico derivado do encéfalo
Brain-derived neurotrophic factor
Tropomyosin receptor kinase B
Neurotrophin
Medulloblastoma
Brain tumor
Texto completo:http://hdl.handle.net/10183/197545
País:Brasil
Oai:oai:www.lume.ufrgs.br:10183/197545

Texto Completo

http://hdl.handle.net/10183/197545

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