Simultaneous determination of candesartan and hydrochlorothiazide in human plasma by LC-MS/MS

A simple, sensitive, rapid and highly efficient LC-MS/MS method was developed for the determination of Candesartan and Hydrochlorothiazide simultaneously in human plasma. The method employed Zorbax eclipse C18 (150 X 4.6 mm, 5µ) column using acetate buffer: acetonitrile (25:75%, v/v) as the mobile p...

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Bibliographic Details
Main Author: Bonthu, Mohan Gandhi (author)
Other Authors: Atmakuri, Lakshmana Rao (author), Jangala, Venkateswara Rao (author)
Format: article
Language:eng
Published: 2018
Subjects:
Candesartan
Hydrochlorothiazide
LC-MS/MS
Method validation
Human plasma.
Online Access:https://doi.org/10.1590/s2175-97902018000117381
Country:Brazil
Oai:oai:revistas.usp.br:article/146841

Internet

https://doi.org/10.1590/s2175-97902018000117381

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