Polyketides from the marine sponge Plakortis angulospiculatus

Organic extracts of the marine sponge Plakortis angulospiculatus were studied from two different collections from Pernambuco State, Brazil. Bioautography with opportunistic marine pathogens, with results from the brine shrimp lethality assay, were used to guide the purification of the known furanyli...

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Bibliographic Details
Main Author: Epifanio,Rosângela de A. (author)
Other Authors: Pinheiro,Leandro S. (author), Alves,Natalia C. (author)
Format: article
Language:eng
Published: 2005
Subjects:
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000800010
Country:Brazil
Oai:oai:scielo:S0103-50532005000800010
Description
Summary:Organic extracts of the marine sponge Plakortis angulospiculatus were studied from two different collections from Pernambuco State, Brazil. Bioautography with opportunistic marine pathogens, with results from the brine shrimp lethality assay, were used to guide the purification of the known furanylidenic methyl ester 1 and two new derivatives 2 and 3. The structures were elucidated by spectroscopic methods and by selective reduction of 3 into 2.