Cochlea cell-specific marker expression upon in vitro Hes1 knockdown

NOTCH pathway proteins, including the transcriptional factor HES1, play crucial roles in the development of the inner ear by means of the lateral inhibition mechanism, in which supporting cells have their phenotype preserved while they are prevented from becoming hair cells. Genetic manipulation of...

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Detalhes bibliográficos
Autor principal: Batissoco,A.C. (author)
Outros Autores: Lezirovitz,K. (author), Zanatta,D.B. (author), Hemza,C.R.M.L. (author), Vasques,L.R. (author), Strauss,B.E. (author), Mingroni-Netto,R.C. (author), Haddad,L.A. (author), Bento,R.F. (author), Oiticica,J. (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
shRNA
Hearing loss
Inner hair cells
Organ of Corti
Hes1 knockdown
Lentivirus
Texto completo:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2021000700601
País:Brasil
Oai:oai:scielo:S0100-879X2021000700601

Texto Completo

http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2021000700601

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