Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer
Background Limitless self-renewal is one of the hallmarks of cancer and is attained by telomere maintenance, essentially through telomerase (hTERT) activation. Transcriptional regulation of hTERT is believed to play a major role in telomerase activation in human cancers. Main body The dominant inter...
Autor principal: | |
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Outros Autores: | , , , , |
Formato: | article |
Idioma: | eng |
Publicado em: |
2018
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Assuntos: | |
Texto completo: | http://hdl.handle.net/10400.1/10529 |
País: | Portugal |
Oai: | oai:sapientia.ualg.pt:10400.1/10529 |