Tissue optical clearing as a diagnostic tool for tissue pathology differentiation

With the objective of developing a diagnostic tool, we have used the immersion optical clearing method and studied normal and pathological tissues (cancer, diabetes) under treatment by optical clearing agents (OCAs). In order to quantify pathology status OCA diffusion properties in different tissues...

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Detalhes bibliográficos
Autor principal: Oliveira, Luís (author)
Outros Autores: Carneiro, Isa (author), Carvalho, Sónia (author), Henrique, Rui (author), Tuchina, Daria (author), Timoshina, Polina (author), Bashkatov, Alexey (author), Genina, Elina (author), Tuchin, Valery (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2018
Assuntos:
Optical clearing
Pathology
Diabetes
Cancer
Free and bound water
Diffusion coefficient
Pathology diagnosis
Texto completo:http://hdl.handle.net/10400.22/11856
País:Portugal
Oai:oai:recipp.ipp.pt:10400.22/11856
Descrição
Resumo:With the objective of developing a diagnostic tool, we have used the immersion optical clearing method and studied normal and pathological tissues (cancer, diabetes) under treatment by optical clearing agents (OCAs). In order to quantify pathology status OCA diffusion properties in different tissues were measured. We have demonstrated that free water content in cancerous tissues is higher than in normal.

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