Multiple domain insertions and losses in the evolution of the Rab prenylation complex

BACKGROUND: Rab proteins are regulators of vesicular trafficking, requiring a lipid modification for proper function, prenylation of C-terminal cysteines. This is catalysed by a complex of a catalytic heterodimer (Rab Geranylgeranyl Transferase - RabGGTase) and an accessory protein (Rab Escort Prote...

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Bibliographic Details
Main Author: Rasteiro, R. (author)
Other Authors: Pereira Leal, J.B. (author)
Format: article
Language:eng
Published: 2009
Subjects:
Protein Prenylation
Protein Structure, Tertiary
rab GTP-Binding Proteins/genetics
Gene Duplication
Evolution, Molecular
Alkyl and Aryl Transferases/genetics
Online Access:http://hdl.handle.net/10400.7/59
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/59

Internet

http://hdl.handle.net/10400.7/59

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