P-cadherin functional role is dependent on E-cadherin cellular context: a proof of concept using the breast cancer model

P-cadherin overexpression is associated with worse breast cancer survival, being a poor prognostic marker as well as a putative therapeutic target for the aggressive triple-negative and basal-like carcinomas (TNBCs). Previously, we have shown that P-cadherin promotes breast cancer invasion of cells...

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Bibliographic Details
Main Author: Ribeiro, Ana Sofia (author)
Other Authors: Sousa, Bárbara (author), Carreto, Laura (author), Mendes, Nuno (author), Nobre, Ana Rita (author), Ricardo, Sara (author), Albergaria, André (author), Cameselle-Teijeiro, Jorge F. (author), Gerhard, Rene (author), Söderberg, Ola (author), Seruca, Raquel (author), Santos, Manuel A. (author), Schmitt, Fernando (author), Paredes, Joana (author)
Format: article
Language:eng
Published: 2018
Subjects:
E-cadherin
P-cadherin
breast cancer
invasion
motility
Online Access:http://hdl.handle.net/10773/24307
Country:Portugal
Oai:oai:ria.ua.pt:10773/24307

Internet

http://hdl.handle.net/10773/24307

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