Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells

KRAS and BRAF mutations are frequent in colorectal carcinoma (CRC) and have the potential to activate proliferation and survival through MAPK/ERK and/or PI3K signalling pathways. Because diet is one of the most important determinants of CRC incidence and progression, we studied the effects of the di...

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Detalhes bibliográficos
Autor principal: Xavier, Cristina P. R. (author)
Outros Autores: Lima, Cristóvão F. (author), Preto, Ana (author), Seruca, Raquel (author), Ferreira, Manuel Fernandes (author), Wilson, Cristina Pereira (author)
Formato: article
Idioma:eng
Publicado em: 2009
Assuntos:
Flavonoids
Ursolic acid
Colorectal carcinoma
MAPK/ERK and PI3K pathways
Molecular nutrition
Science & Technology
Texto completo:https://hdl.handle.net/1822/12236
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/12236

Texto Completo

https://hdl.handle.net/1822/12236

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