Study of lipid alterations related with Alzheimer disease

Alzheimer disease is characterized by defects in the signaling mediated by acetylcholine. Tacrine was used as acetylcholinesterase (AChE) inhibitor approved for the treatment of Alzheimer’s disease. However, tacrine treatment has some toxicological effects associated with mitochondrial dysfunction,...

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Bibliographic Details
Main Author: Melo, Tânia Sofia Rodrigues de (author)
Format: masterThesis
Language:eng
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10773/7547
Country:Portugal
Oai:oai:ria.ua.pt:10773/7547