Study of lipid alterations related with Alzheimer disease
Alzheimer disease is characterized by defects in the signaling mediated by acetylcholine. Tacrine was used as acetylcholinesterase (AChE) inhibitor approved for the treatment of Alzheimer’s disease. However, tacrine treatment has some toxicological effects associated with mitochondrial dysfunction,...
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Format: | masterThesis |
Language: | eng |
Published: |
2012
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Online Access: | http://hdl.handle.net/10773/7547 |
Country: | Portugal |
Oai: | oai:ria.ua.pt:10773/7547 |