Evaluation of toxic/protective effects of the essential oil of Salvia officinalis on freshly isolated rat hepatocytes

For this study the essential oil (EO) of sage (Salvia officinalis L.) was isolated from air-dried vegetative aerial parts of the plants by hydrodistillation and analysed by GC and GC-MS. A total yield of 12.07 mg of EO per g of plant dry mass was obtained and more than 50 compounds identified. The m...

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Bibliographic Details
Main Author: Lima, Cristóvão F. (author)
Other Authors: Carvalho, Felix (author), Fernandes, Eduarda (author), Bastos, Maria de Lurdes (author), Gomes, P. Santos (author), Ferreira, Manuel Fernandes (author), Wilson, Cristina Pereira (author)
Format: article
Language:eng
Published: 2004
Subjects:
Salvia officinalis
Sage
Essential oil
Toxic effects
Antioxidant effects
Hepatoprotective effects
Hepatocytes
DMSO - dimethyl sulfoxide
EO - essential oil
GC - gas chromatography
GC-MS - GC coupled to mass spectrometry
GSH - reduced glutathione
GSSG - oxidised glutathione
GSx - total glutathione
LDH - lactate dehydrogenase
Science & Technology
Online Access:http://hdl.handle.net/1822/4136
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/4136

Internet

http://hdl.handle.net/1822/4136

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