A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

Parkinson's Disease (PD) is a neurodegenerative disorder affecting more than 10 million people worldwide. Currently, PD has no cure and no early diagnostics methods exist. Mitochondrial dysfunction is presented in the early stages of PD, and it is considered an important pathophysiology compone...

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Detalhes bibliográficos
Autor principal: Deus, Cláudia M. (author)
Outros Autores: Pereira, Susana P. (author), Cunha-Oliveira, Teresa (author), Teixeira, José (author), Simões, Rui F. (author), Cagide, Fernando (author), Benfeito, Sofia (author), Borges, Fernanda (author), Raimundo, Nuno (author), Oliveira, Paulo J. (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Human skin fibroblasts
Metabolism
Mitochondria
Mitochondriotropic antioxidant
Sporadic Parkinson's disease
Caffeic Acids
Fibroblasts
Humans
Male
Oxidative Stress
Parkinson Disease
Texto completo:http://hdl.handle.net/10316/101011
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/101011

Texto Completo

http://hdl.handle.net/10316/101011

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