Analysis of the 5’ untranslated region of human UPF1 mRNA indicates both cryptic promoter and internal ribosome entry site activity

Apart from its role in nonsense-mediated mRNA decay, a mechanism that promotes rapid degradation of transcripts carrying premature translation termination codons, the human up-frameshift 1 (UPF1) DNA and RNA helicase protein plays a crucial role in telomere replication and homeostasis, and in cell c...

ver descrição completa

Detalhes bibliográficos
Autor principal: Lacerda, Rafaela (author)
Outros Autores: Marques-Ramos, Ana (author), Teixeira, Alexandre (author), Romão, Luísa (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2015
Assuntos:
Texto completo:http://hdl.handle.net/10400.18/2715
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2715