Synthesis of new glycosylated flavonoids with inhibitory activity on cell growth

Natural flavonoids and xanthone glycosides display several biological activities, with the glycoside moiety playing an important role in the mechanism of action of these metabolites. Herein, to give further insights into the inhibitory activity on cell growth of these classes of compounds, the synth...

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Bibliographic Details
Main Author: Neves A.R. (author)
Other Authors: Correia-da-Silva M. (author), Silva P.M.A. (author), Ribeiro D. (author), Sousa E. (author), Bousbaa H. (author), Pinto M. (author)
Format: article
Language:eng
Published: 2018
Subjects:
acetic anhydride
antineoplastic agent
flavonoid
xanthone
xanthone derivative
acetylation
astrocyte
cell survival
chemistry
drug design
drug effect
epithelium cell
glia
glycosylation
human
IC50
MCF-7 cell line
microwave radiation
pathology
structure activity relation
synthesis
tumor cell line
Acetic Anhydrides
Acetylation
Antineoplastic Agents
Astrocytes
Cell Line, Tumor
Cell Survival
Drug Design
Epithelial Cells
Flavonoids
Glycosylation
Humans
Inhibitory Concentration 50
MCF-7 Cells
Microwaves
Neuroglia
Structure-Activity Relationship
Xanthones
Online Access:https://hdl.handle.net/10216/120499
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/120499

Internet

https://hdl.handle.net/10216/120499

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