Bilayered chitosan-based scaffolds for osteochondral tissue engineering : influence of hydroxyapatite on in vitro cytotoxicity and dynamic bioactivity studies in a specific double-chamber bioreactor

Osteochondral tissue engineering presents a current research challenge due to the necessity of combining both bone and cartilage tissue engineering principles. In the present study, bilayered chitosan-based scaffolds are developed based on the optimization of both polymeric and composite scaffolds....

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Bibliographic Details
Main Author: Malafaya, P. B. (author)
Other Authors: Reis, R. L. (author)
Format: article
Language:eng
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1822/20358
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/20358