Redox-responsive alginate nanogels with enhanced anticancer cytotoxicity

Although doxorubicin (Dox) has been widely used in the treatment of different types of cancer, its insufficient cellular uptake and intracellular release is still a limitation. Herein, we report an easy process for the preparation of redox-sensitive nanogels that were shown to be highly efficient in...

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Detalhes bibliográficos
Autor principal: Maciel, Dina (author)
Outros Autores: Figueira, Priscilla (author), Xiao, Shili (author), Hu, Dengmai (author), Shi, Xiangyang (author), Rodrigues, João (author), Tomás, Helena (author), Li, Yulin (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Absorption
Alginates
Antibiotics, Antineoplastic
Cell line, Tumor
Cell shape
Cell survival
Doxorubicin
Drug carriers
Humans
Kinetics
Nanostructures
Oxidation-reduction
Spectroscopy, Fourier Transform Infrared
.
Faculdade de Ciências Exatas e da Engenharia
Texto completo:http://hdl.handle.net/10400.13/2414
País:Portugal
Oai:oai:digituma.uma.pt:10400.13/2414

Texto Completo

http://hdl.handle.net/10400.13/2414

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