Redox-responsive alginate nanogels with enhanced anticancer cytotoxicity

Although doxorubicin (Dox) has been widely used in the treatment of different types of cancer, its insufficient cellular uptake and intracellular release is still a limitation. Herein, we report an easy process for the preparation of redox-sensitive nanogels that were shown to be highly efficient in...

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Bibliographic Details
Main Author: Maciel, Dina (author)
Other Authors: Figueira, Priscilla (author), Xiao, Shili (author), Hu, Dengmai (author), Shi, Xiangyang (author), Rodrigues, João (author), Tomás, Helena (author), Li, Yulin (author)
Format: article
Language:eng
Published: 2019
Subjects:
Absorption
Alginates
Antibiotics, Antineoplastic
Cell line, Tumor
Cell shape
Cell survival
Doxorubicin
Drug carriers
Humans
Kinetics
Nanostructures
Oxidation-reduction
Spectroscopy, Fourier Transform Infrared
.
Faculdade de Ciências Exatas e da Engenharia
Online Access:http://hdl.handle.net/10400.13/2414
Country:Portugal
Oai:oai:digituma.uma.pt:10400.13/2414

Internet

http://hdl.handle.net/10400.13/2414

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