Functional analyses of inclusion membrane proteins of Chlamydia trachomatis

Chlamydia trachomatis belongs to a group of highly related obligate intracellular bacteria. It is the etiological agent of important human sexually transmitted infections and trachoma. C. trachomatis strains can be divided in the trachoma biovar, which includes strains that cause noninvasive infecti...

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Bibliographic Details
Main Author: Almeida, Filipe Manuel Baeta da Silva (author)
Format: doctoralThesis
Language:eng
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/10362/55744
Country:Portugal
Oai:oai:run.unl.pt:10362/55744
Description
Summary:Chlamydia trachomatis belongs to a group of highly related obligate intracellular bacteria. It is the etiological agent of important human sexually transmitted infections and trachoma. C. trachomatis strains can be divided in the trachoma biovar, which includes strains that cause noninvasive infections of conjunctival and genital epithelial cells (ocular and urogenital strains, respectively), and the lymphogranuloma venereum (LGV) biovar, which is responsible for a more invasive disease, and includes strains that are able to infect macrophages and disseminate into lymph nodes (LGV strains).