Synthesis, structure and antileishmanial evaluation of endoperoxide–pyrazole hybrids

Leishmaniases are among the most impacting neglected tropical diseases. In attempts to repurpose antimalarial drugs or candidates, it was found that selected 1,2,4-trioxanes, 1,2,4,5-tetraoxanes, and pyrazole-containing chemotypes demonstrated activity against <i>Leishmania</i> parasites...

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Bibliographic Details
Main Author: Amado, Patrícia S. M. (author)
Other Authors: Costa, Inês C. C. (author), Paixão, José A. (author), Mendes, Ricardo F. (author), Cortes, Sofia (author), Cristiano, Maria L. (author)
Format: article
Language:eng
Published: 2022
Subjects:
Antileishmanial chemotherapy
1,2,4-trioxanes
1,2,4,5-tetraoxanes
Pyrazoles
Endoperoxide– pyrazole hybrids
Prototropic tautomerism
Online Access:http://hdl.handle.net/10400.1/18238
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/18238

Internet

http://hdl.handle.net/10400.1/18238

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