In vivo targeted gene delivery to peripheral neurons mediated by neurotropic poly(ethylene imine)-based nanoparticles

A major challenge in neuronal gene therapy is to achieve safe, efficient, and minimally invasive transgene delivery to neurons. In this study, we report the use of a nonviral neurotropic poly(ethylene imine)-based nanoparticle that is capable of mediating neuron-specific transfection upon a subcutan...

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Bibliographic Details
Main Author: Lopes, C (author)
Other Authors: Oliveira, H (author), Estevão, I (author), Pires, L (author), Pêgo, AP (author)
Format: article
Language:eng
Published: 2016
Subjects:
Gene therapy
Neuron-targeted
Nonviral vector
Peripheral neurons
Online Access:https://hdl.handle.net/10216/120741
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/120741

Internet

https://hdl.handle.net/10216/120741

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