Sitagliptin ameliorates kidney lesions in a rat model of type 2 diabetes due to anti-inflammatory and anti-apoptotic effects

Objective: This study aimed to evaluate the efficacy of sitagliptin, a dipeptidyl peptidase IV (DPP-IV) inhibitor, in preventing the deleterious effects of diabetes on the kidney in an animal model of T2DM, the Zucker Diabetic Fatty (ZDF) rat. Methods: ZDF rats (aged 20 weeks) were treated with sita...

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Bibliographic Details
Main Author: Marques, C. (author)
Other Authors: Mega, C. (author), Gonçalves, A. (author), Rodrigues-Santos, P. (author), Vala, Helena (author), Teixeira-Lemos, E. (author), Teixeira, F. (author), Fontes-Ribeiro, C. (author), Reis, F. (author), Fernandes, R. (author)
Format: conferenceObject
Language:eng
Published: 2015
Subjects:
sitagliptin
Zucker Diabetic Fatty (ZDF) rat
animal model of T2DM
dipeptidyl peptidase IV (DPP-IV) inhibitor
Online Access:http://hdl.handle.net/10400.19/2715
Country:Portugal
Oai:oai:repositorio.ipv.pt:10400.19/2715

Internet

http://hdl.handle.net/10400.19/2715

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