Development of a framework for metabolic pathway analysis-driven strain optimization methods

Genome-scale metabolic models (GSMMs) have become important assets for rational design of compound overproduction using microbial cell factories. Most computational strain optimization methods (CSOM) using GSMMs, while useful in metabolic engineering, rely on the definition of questionable cell obje...

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Detalhes bibliográficos
Autor principal: Vieira, Vítor (author)
Outros Autores: Maia, Paulo (author), Rocha, Isabel (author), Rocha, Miguel (author)
Formato: article
Idioma:eng
Publicado em: 2017
Assuntos:
Constraint-based modeling
Metabolic engineering
Pathway analysis
Minimal cut sets
Strain optimization
Science & Technology
Texto completo:http://hdl.handle.net/1822/46347
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/46347

Texto Completo

http://hdl.handle.net/1822/46347

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