Development of a framework for metabolic pathway analysis-driven strain optimization methods

Genome-scale metabolic models (GSMMs) have become important assets for rational design of compound overproduction using microbial cell factories. Most computational strain optimization methods (CSOM) using GSMMs, while useful in metabolic engineering, rely on the definition of questionable cell obje...

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Bibliographic Details
Main Author: Vieira, Vítor (author)
Other Authors: Maia, Paulo (author), Rocha, Isabel (author), Rocha, Miguel (author)
Format: article
Language:eng
Published: 2017
Subjects:
Constraint-based modeling
Metabolic engineering
Pathway analysis
Minimal cut sets
Strain optimization
Science & Technology
Online Access:http://hdl.handle.net/1822/46347
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/46347

Internet

http://hdl.handle.net/1822/46347

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