Combinatorial delivery of Crizotinib–Palbociclib–Sildenafil using TPGS-PLA micelles for improved cancer treatment

The co-delivery of multiple chemotherapeutics by micellar delivery systems is a valuable approach to improve cancer treatment since various disease hallmarks can be targeted simultaneously. However, the delivery of multiple drugs requires a nanocarrier structure that can encapsulate various bioactiv...

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Bibliographic Details
Main Author: Diogo, Duarte Miguel de Melo (author)
Other Authors: Gaspar, Vítor Manuel Abreu (author), Costa, Elisabete Cristina da Rocha (author), Moreira, André Ferreira (author), Oppolzer, David Jerónimo (author), Gallardo, Eugenia (author), Correia, Ilídio Joaquim Sobreira (author)
Format: article
Language:eng
Published: 2018
Subjects:
Cancer
Co-delivery
Micellar carriers
Multidrug therapy
Non-small cell lung cancer
TPGS-PLA copolymer
Online Access:http://hdl.handle.net/10400.6/4657
Country:Portugal
Oai:oai:ubibliorum.ubi.pt:10400.6/4657

Internet

http://hdl.handle.net/10400.6/4657

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