Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage

INTRODUCTION: Disorders that affect glucose metabolism, namely diabetes mellitus (DM), may favor the development and/or progression of osteoarthritis (OA). Thus far, little is known regarding the ability of chondrocytes to adjust to variations in the extracellular glucose concentration, resulting fr...

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Bibliographic Details
Main Author: Rosa, SC (author)
Other Authors: Gonçalves, J (author), Judas, F (author), Mobasheri, A (author), Lopes, C (author), Mendes, AF (author)
Format: article
Language:eng
Published: 2011
Subjects:
Cartilagem Articular
Osteoartrite
Glucose
Stress Oxidativo
Online Access:http://hdl.handle.net/10400.4/1180
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/1180

Internet

http://hdl.handle.net/10400.4/1180

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