γδ-T cells promote IFN-γ–dependent Plasmodium pathogenesis upon liver-stage infection

Cerebral malaria (CM) is a major cause of death due to Plasmodium infection. Both parasite and host factors contribute to the onset of CM, but the precise cellular and molecular mechanisms that contribute to its pathogenesis remain poorly characterized. Unlike conventional αβ-T cells, previous studi...

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Detalhes bibliográficos
Autor principal: Ribot, Julie C. (author)
Outros Autores: Neres, Rita (author), Zuzarte-Luís, Vanessa (author), Gomes, Anita Quintal (author), Mancio-Silva, Liliana (author), Mensurado, Sofia (author), Pinto-Neves, Daniel (author), Santos, Miguel M. (author), Carvalho, Tânia (author), Landry, Jonathan J. M. (author), Rolo, Eva A. (author), Malik, Ankita (author), Silva, Daniel Varón (author), Mota, Maria M. (author), Silva-Santos, Bruno (author), Pamplona, Ana (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Plasmodium
Cerebral malaria
Gamma-delta T cells
Interferon-gamma
Liver stage
Texto completo:http://hdl.handle.net/10400.21/10008
País:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/10008

Texto Completo

http://hdl.handle.net/10400.21/10008

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