γδ-T cells promote IFN-γ–dependent Plasmodium pathogenesis upon liver-stage infection

Cerebral malaria (CM) is a major cause of death due to Plasmodium infection. Both parasite and host factors contribute to the onset of CM, but the precise cellular and molecular mechanisms that contribute to its pathogenesis remain poorly characterized. Unlike conventional αβ-T cells, previous studi...

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Bibliographic Details
Main Author: Ribot, Julie C. (author)
Other Authors: Neres, Rita (author), Zuzarte-Luís, Vanessa (author), Gomes, Anita Quintal (author), Mancio-Silva, Liliana (author), Mensurado, Sofia (author), Pinto-Neves, Daniel (author), Santos, Miguel M. (author), Carvalho, Tânia (author), Landry, Jonathan J. M. (author), Rolo, Eva A. (author), Malik, Ankita (author), Silva, Daniel Varón (author), Mota, Maria M. (author), Silva-Santos, Bruno (author), Pamplona, Ana (author)
Format: article
Language:eng
Published: 2019
Subjects:
Plasmodium
Cerebral malaria
Gamma-delta T cells
Interferon-gamma
Liver stage
Online Access:http://hdl.handle.net/10400.21/10008
Country:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/10008

Internet

http://hdl.handle.net/10400.21/10008

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