Glycoprotein Non-Metastatic Protein B: an Emerging Biomarker for Lysosomal Dysfunction in Macrophages

Several diseases are caused by inherited defects in lysosomes, the so-called lysosomal storage disorders (LSDs). In some of these LSDs, tissue macrophages transform into prominent storage cells, as is the case in Gaucher disease. Here, macrophages become the characteristic Gaucher cells filled with...

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Bibliographic Details
Main Author: van der Lienden, Martijn (author)
Other Authors: Gaspar, Paulo (author), Boot, Rolf (author), Aerts, Johannes (author), van Eijk, Marco (author)
Format: article
Language:eng
Published: 2019
Subjects:
GPNMB
MITF
Autophagy
Foam Cell
Inflammation
Lysosomal Storage Disorders
Lysosome
Macrophage
Metabolic Syndrome
Phagocytosis
Doenças Genéticas
Online Access:http://hdl.handle.net/10400.18/6262
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6262

Internet

http://hdl.handle.net/10400.18/6262

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