A 17-mer Membrane-Active MSI-78 Derivative with Improved Selectivity toward Bacterial Cells

Antimicrobial peptides are widely recognized as an excellent alternative to conventional antibiotics. MSI-78, a highly effective and broad spectrum AMP, is one of the most promising AMPs for clinical application. In this study, we have designed shorter derivatives of MSI-78 with the aim of improving...

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Bibliographic Details
Main Author: Claudia Monteiro (author)
Other Authors: Marina Pinheiro (author), Mariana Fernandes (author), Silvia Maia (author), Catarina L Seabra (author), Frederico Ferreira da Silva (author), Salette Reis (author), Paula Gomes (author), Cristina C L Martins (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10216/82150
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/82150