Encapsulated bacteriophages in alginate-nanohydroxyapatite hydrogel as a novel delivery system to prevent orthopedic implant-associated infections

An innovative delivery system based on bacteriophages-loaded alginate-nanohydroxyapatite hydrogel was developed as a multifunctional approach for local tissue regeneration and infection prevention and control. Bacteriophages were efficiently encapsulated, without jeopardizing phage viability and fun...

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Bibliographic Details
Main Author: Barros, Joana Alberta Ribeiro (author)
Other Authors: Melo, Luís Daniel Rodrigues de (author), Silva, Rita Araújo Reis da (author), Ferraz, Maria Pia (author), Azeredo, Joana Cecília Valente de Rodrigues (author), Pinheiro, Victor Manuel de Carvalho (author), Colaço, Bruno Jorge Antunes (author), Fernandes, Maria Helena Raposo (author), Gomes, Pedro de Sousa (author), Monteiro, Fernando Jorge (author)
Format: article
Language:eng
Published: 2020
Subjects:
Bacteriophages
Alginate-nanohydroxyapatite
Biocompatibility
Antimicrobial activity
Osteogenic differentiation
Online Access:http://hdl.handle.net/10284/8498
Country:Portugal
Oai:oai:bdigital.ufp.pt:10284/8498

Internet

http://hdl.handle.net/10284/8498

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