Optimising the production of a silk-elastin-like protein in E. coli: overcoming acetate accumulation and plasmid instability

Silk-elastin-like proteins (SELPs) combining the physicochemical and biological properties of silk and elastin have a high potential for use in the pharmaceutical, regenerative medicine and materials fields. Their development for use is however restrained by their production levels. Here we describe...

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Bibliographic Details
Main Author: Collins, Tony (author)
Other Authors: Barroca, Mário Jorge Faria (author), Branca, Fernando (author), Silva, João Azevedo (author), Costa, André da (author), Machado, Raul (author), Casal, Margarida (author)
Format: conferencePoster
Language:eng
Published: 2013
Subjects:
protein based polymers
silk-elastin-like polymers
production optimisation
batch and fed-batch production
pET-E. coli BL21(DE3)
Online Access:http://hdl.handle.net/1822/31017
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/31017

Internet

http://hdl.handle.net/1822/31017

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