tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast

Protein synthesis rate and accuracy are tightly controlled by the cell and are essential for proteome homoeostasis (proteostasis); however, the full picture of how mRNA translational factors maintain protein synthesis accuracy and co-translational protein folding are far from being fully understood....

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Bibliographic Details
Main Author: Tavares, Joana F. (author)
Other Authors: Davis, Nick K. (author), Poim, Ana (author), Reis, Andreia (author), Kellner, Stefanie (author), Sousa, Inês (author), Soares, Ana R. (author), Moura, Gabriela M. R. (author), Dedon, Peter C. (author), Santos, Manuel (author)
Format: article
Language:eng
Published: 2021
Subjects:
(5-10) tRNA modifying enzymes
Protein aggregation
Yeast
tRNA
Proteome
Online Access:http://hdl.handle.net/10773/30815
Country:Portugal
Oai:oai:ria.ua.pt:10773/30815

Internet

http://hdl.handle.net/10773/30815

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