Identification of an IRES element in the human mTOR transcript: its structural and functional features
Mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates signals from the cellular nutrient- and energy-status, acting namely on the protein synthesis machinery. Deregulation of mTOR signaling is implicated in major diseases, such as cancer, mainly due to its role...
Autor principal: | |
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Outros Autores: | , , , |
Formato: | conferenceObject |
Idioma: | eng |
Publicado em: |
2015
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Assuntos: | |
Texto completo: | http://hdl.handle.net/10400.18/2718 |
País: | Portugal |
Oai: | oai:repositorio.insa.pt:10400.18/2718 |