Identification of an IRES element in the human mTOR transcript: its structural and functional features

Mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates signals from the cellular nutrient- and energy-status, acting namely on the protein synthesis machinery. Deregulation of mTOR signaling is implicated in major diseases, such as cancer, mainly due to its role...

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Bibliographic Details
Main Author: Marques-Ramos, Ana (author)
Other Authors: Menezes, Juliane (author), Lacerda, Rafaela (author), Teixeira, Alexandre (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2015
Subjects:
Genómica Funcional
Mammalian Target of Rapamycin (mTOR)
Internal Ribosome Entry Site (IRES)
mRNA Translation
Online Access:http://hdl.handle.net/10400.18/2718
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2718

Internet

http://hdl.handle.net/10400.18/2718

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