Gold compounds inhibit the Ca2+-ATPase activity of brain PMCA and human neuroblastoma SH-SY5Y cells and decrease cell viability

Plasma membrane calcium ATPases (PMCA) are key proteins in the maintenance of calcium (Ca<sup>2+</sup>) homeostasis. Dysregulation of PMCA function is associated with several human pathologies, including neurodegenerative diseases, and, therefore, these proteins are potential drug target...

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Bibliographic Details
Main Author: Berrocal, Maria (author)
Other Authors: Cordoba-Granados, Juan J. (author), Carabineiro, Sónia A. C. (author), Gutierrez-Merino, Carlos (author), Aureliano, Manuel (author), Mata, Ana M. (author)
Format: article
Language:eng
Published: 2022
Subjects:
Gold compounds
PMCA
Ca2+-ATPase
Calcium homeostasis
SH-SY5Y human neuroblastoma cells
Online Access:http://hdl.handle.net/10400.1/17459
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/17459

Internet

http://hdl.handle.net/10400.1/17459

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