Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum

Cationic liposome-DNA complexes ([`]lipoplexes') are used as gene delivery vehicles and may overcome some of the limitations of viral vectors for gene therapy applications. The interaction of highly positively charged lipoplexes with biological macromolecules in blood and tissues is one of the...

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Detalhes bibliográficos
Autor principal: Simões, Sérgio (author)
Outros Autores: Slepushkin, Vladimir (author), Pires, Pedro (author), Gaspar, Rogério (author), Pedroso de Lima, Maria C. (author), Düzgünes, Nejat (author)
Formato: article
Idioma:eng
Publicado em: 2000
Assuntos:
Texto completo:http://hdl.handle.net/10316/5812
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5812