Targeting of lanthanide(III) chelates of DOTA-type glycoconjugates to the hepatic asyaloglycoprotein receptor: cell internalization and animal imaging studies

The characterization of a new class of hydrophilic liver-targeted agents for gamma-scintigraphy and MRI, consisting, respectively, of [153Sm]3+ or Gd3+ complexes of DOTA monoamide or bisamide linked glycoconjugates (DOTA = 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid), is reported. In vi...

ver descrição completa

Detalhes bibliográficos
Autor principal: Prata, M. I. M. (author)
Outros Autores: Santos, A. C. (author), Torres, Susana (author), André, João P. (author), Martins, J. A. R. (author), Neves, M. (author), García Martín, M. L. (author), Rodrigues, T. B. (author), López Larrubia, P. (author), Cerdán, S. (author), Geraldes, Carlos F. G. C. (author)
Formato: article
Idioma:eng
Publicado em: 2006
Assuntos:
Magnetic resonance imaging
Contrast agents
Gadolinium
Glycoconjugates
Liver targeting
Asialoglycoprotein receptor
Gamma imaging
gamma scintigraphy
Science & Technology
Texto completo:http://hdl.handle.net/1822/5960
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/5960

Texto Completo

http://hdl.handle.net/1822/5960

Registros relacionados