Cysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer

The authors would like to acknowledge the Instituto Português de Oncologia de Lisboa Francisco Gentil (IPOLFG) for partially funding the project. The study was also funded by Projecto TVI. This research was supported by Fundação para a Ciência e Tecnologia (FCT) (PhD ProRegeM program, PD/BD/105893/2...

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Bibliographic Details
Main Author: Nunes, Sofia C. (author)
Other Authors: Lopes-Coelho, Filipa (author), Gouveia-Fernandes, Sofia (author), Ramos, Cristiano (author), Pereira, Sofia A. (author), Serpa, Jacinta (author)
Format: article
Language:eng
Published: 2018
Subjects:
Chemoresistance
Cysteine
Evolutionary trade-off
Hypoxia
Metabolic selection
Ovarian cancer
Ecology, Evolution, Behavior and Systematics
SDG 3 - Good Health and Well-being
Online Access:https://doi.org/10.1186/s12862-018-1214-1
Country:Portugal
Oai:oai:run.unl.pt:10362/41064
Description
Summary:The authors would like to acknowledge the Instituto Português de Oncologia de Lisboa Francisco Gentil (IPOLFG) for partially funding the project. The study was also funded by Projecto TVI. This research was supported by Fundação para a Ciência e Tecnologia (FCT) (PhD ProRegeM program, PD/BD/105893/2014) and iNOVA4Health.

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